Taken 2048 as an example, I have tried unsuccessfully to load it on the real machine from floppy, SD-reader or SF3 USB. It also doesn't work on the CPC.
But it is an exceptional case, other few games don't work for other causes. Some only work on 16 colours, even one only with the V9990 cartridge, I mean Flappybird.
I still have have not tried all the games, but GameOfLife, Pac-Man and Doom work for me.
I have compiled the 2048 source with the latest Quigs version and now it seems to work. Can you test it?
Edit: the new 2048 can't be closed on the X corner... You can close it from the Task Manager(Start/Security/Task Manager): click on SymbOS Application on the list of Apps and then click on the "End App." button. It is the same like in Windows with Ctl+Alt+Del.