I think that the Enterprise is not so powerful to manage an effects full loaded Midi song, mainly because its Serial port is software driven. But this has to be probed practically, because on many other aspects it has surprised us. Before reading this article I didn't know that the Enterprise serial port was able to reach 31250 baud/sec....
This approach can have some incompatibility with EnterMice, as the RTS line at the Serial port is also used for mouse comunication, theoretically only while a mouse channel is open.
I still have not played with this project because is somewhat incomplete. But although incomplete, I think there is sufficient information to make a little Basic program to test some notes.